What is Azoospermia?

Meaning and Definition of Azoospermia

Azoospermia is a condition in which spermatozoa are not observed in the ejaculation process and is an important cause of male infertility depending on the case.

It obeys two fundamental causes . For one, there is a change in sperm production known as secretory azoospermia . On the other hand, even with normal sperm production there is a change in the tubes leading from semen to the urethra called obstructive azoospermia.

There are a variety of causes that lead to the onset of azoospermia, and it is even possible for this condition to be intermittent. In some ejaculations the semen lacks sperm while in others the sperm content is normal and even high.

There are also situations in which azoospermia is reversible and this occurs as a consequence of a transitory situation. The use of some medications and treatments such as radio or chemotherapy , including the course of infections that accompany very high fever.

Types of Azoospermia

Production Failures

This type of azoospermia is due to a large number of causes that cause there to be no sperm production in the testicle.

These causes bring with them disorders such as some genetic faults. They include Klinefelter syndrome, where even with their outward appearance as a man, genetically the individual is not XY. Rather, he has chromosomal variants like XXY that affect his testosterone production . Another genetic cause is alterations of the Y chromosome.

It is also possible that azoospermia is due to the lack of development of the testicles or even their absence or, due to the fact that they are injured and stop working due to trauma, due to changes in the circulation as in the case of a testicular torsion or as a sequel to infections resulting in testicular inflammation known as orchitis .


In this type of azoospermia , sperm production is normal, however it affects a route that follows the sperm from the testis to the urethra for elimination, known as the seminal route .

It is also possible that it affects the release of sperm in situations that lead to ejaculation. Spinal cord injuries or retrograde ejaculation conditions where semen does not come out and remains in the bladder. Phenomenon that is related to certain disorders such as diabetes.

Treatment of Azoospermia

Often the cause of azoospermia is not treated. There are medical and surgical procedures that allow these men to have healthy genetic children, especially when it comes to obstructive azoospermia that obtains sperm from the testicle and even freezes them to be used later in an insemination procedure.

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